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Year : 2022  |  Volume : 36  |  Issue : 3  |  Page : 243-250

Advances in retinopathy of prematurity imaging

1 Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
2 Department of Ophthalmology, Oregon Health and Science University, Portland, Oregon, USA
3 Retina and Vitreous of Texas, Houston, Texas, USA
4 Department of Ophthalmology, Shiley Eye Institute, University of California, San Diego, California, USA

Correspondence Address:
Dr. Yoshihiro Yonekawa
Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/sjopt.sjopt_20_22

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Retinopathy of prematurity (ROP) remains the leading cause of childhood blindness worldwide. Recent advances in ROP imaging have significantly improved our understanding of the pathogenesis and pathophysiological course of ROP including the acute phase, regression, reactivation, and late complications, known as adult ROP. Recent progress includes various contact and noncontact wide-field imaging devices for fundus imaging, smartphone-based fundus photography, wide-field fluorescein angiography, handheld optical coherence tomography (OCT) devices for wide-field en face OCT images, and OCT angiography. Images taken by those devices were incorporated in the recently updated guidelines of ROP, the International Classification of Retinopathy of Prematurity, Third Edition (ICROP3). ROP imaging has also allowed the real-world adoption of telemedicine- and artificial intelligence (AI)-based screening. Recent study demonstrated proof of concept that AI has a high diagnostic performance for the detection of ROP in a real-world screening. Here, we summarize the recent advances in ROP imaging and their application for screening, diagnosis, and management of ROP.

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